The Israeli military said on Tuesday that missiles had been launched from Iran towards Israel, and that its home front command had provided life-saving guidelines to people in various parts of the country.
Earlier, the military had announced that any ballistic missile strike from Iran was expected to be widespread and told the public to shelter in safe rooms in the event of an attack.
The Israeli army also said Israel's airspace was closed following the Iranian attack.
The firing of missiles came after Israeli troops launched ground raids into Lebanon, in the biggest escalation of regional warfare since fighting erupted in Gaza a year ago.
Iran has vowed to retaliate following attacks that killed the top leadership of its Hezbollah allies in Lebanon.
Iran's Revolutionary Guards said the country had launched tens of missiles at Israel, and that if Israel retaliated, Tehran's response would be more crushing.
In Washington, President Joe Biden said the United States was prepared to help Israel defend itself.
Meanwhile, four people were killed and seven wounded in a shooting attack in the Jaffa neighbourhood of Tel Aviv on Tuesday. Israeli police said the two shooters had been "neutralised" and the situation was under control.
One of Afghanistan's worst earthquakes killed more than 800 people and injured at least 2,800, authorities said on Monday, as helicopters ferried the wounded to hospital after they were plucked from the rubble of homes being combed for survivors.
Israel pushed tanks deeper into Gaza City and detonated explosives-laden vehicles in one suburb as airstrikes killed at least 19 people on Monday, Palestinian officials and witnesses said.
India's Narendra Modi told Vladimir Putin on Monday that India and Russia stood shoulder to shoulder even in difficult times after the Kremlin chief cast the Indian prime minister as his "dear friend" and gave him a lift in his armoured limousine.
Chinese President Xi Jinping urged leaders to leverage their "mega-scale market", while Russian President Vladimir Putin showed support for Xi's ambition for a new global security and economic order that poses a challenge to the US during a regional summit on Monday.
South Korea has suspended a military radio broadcast that transmits to North Korea as part of measures aimed at easing tensions with Pyongyang, Seoul's defence ministry said on Monday.