Top seed Karolina Pliskova has crashed out of the US Open following a straight-sets defeat in the second round.
The world no.3 lost 6-1, 7-6 (2) to France’s Caroline Garcia, who will now face 28th seed, American Jennifer Brady.
Elsewhere, sixth seed Petra Kvitova overcame a shaky start to defeat Kateryna Kozlova 7-6 (3), 6-2 in her second-round match, while the 2018 champion, Naomi Osaka, cruised past Camila Giorgi 6-1, 6-2.
In the men’s draw, top seed Novak Djokovic overcame Kyle Edmund 6-7 (7-5), 6-3, 6-4, 6-2 to set up a third-round matchup against No. 28 Jan-Lennard Struff.
Fourth seed Stefanos Tsitsipas also advanced to the third round following a 7-6 (2), 6-3, 6-4 win over wild card Maxime Cressy.


Pogacar wins third Flanders crown but faces fine for running red light
Thuram and Martinez star as Inter dismantle Roma
Silva to exit Man City at end of season, assistant manager confirms
Penalty heroics help Leeds beat West Ham to reach FA Cup semis
Pogačar wins Tour of Flanders for record-equalling third time