England beat Ireland and France by 12 and 36 points respectively in their first two matches of the campaign.
They are currently ranked third in the world.
Play from the Millennium Stadium in Cardiff gets underway at 8:45 PM UAE time.
Meanwhile Scotland travel to France for their latest Six Nations fixture.
Action from the Stade de France starts at 6:15 PM UAE time.
Desert Vipers cruise past Sharjah Warriorz to strengthen table-top push
Desert Vipers continued their strong run in the DP World ILT20 season 4 with a comprehensive victory over Sharjah Warriorz, beating them by four wickets at the Dubai International Stadium on Saturday.
Gill dropped, Kishan back for India's T20 World Cup title defence
Test and one-day captain Shubman Gill could not find a place in India's 15-member squad for next year's home Twenty20 World Cup, but stumper-batter Ishan Kishan returned to the side on Saturday.
Joshua delivers reality check to Paul with sixth-round KO
Former heavyweight champion Anthony Joshua delivered a dose of reality to Jake Paul on Friday with a savage sixth-round knockout in Miami that left the social-media-star-turned prizefighter nursing a suspected broken jaw.
Dubai Capitals assert authority in 63-run win over Sharjah WarriorzÂ
The Dubai Capitals defeated the Sharjah Warriorz for the first time in DP World ILT20 history, with a resounding 63-run victory at the Dubai International Stadium.
Head, Carey push England to the brink in Adelaide
Travis Head and Alex Carey forged a defiant late stand at their home Adelaide Oval on Friday to all but erase England's Ashes hopes, the pair leaning on each other through another draining afternoon in the heat.
For one morning only, you could host the UAE’s biggest radio show, The Kris Fade Show - live across the nation.
It arrived: The UAE's First Mega Music Festival at Expo City Dubai!
The super-star and multi-award-winning singer-songwriter, Jason Derulo is bringing the heat to Dubai.
Hear Maz & James chatting to the featured artists every month with Flash Entertainment.
