England beat Ireland and France by 12 and 36 points respectively in their first two matches of the campaign.
They are currently ranked third in the world.
Play from the Millennium Stadium in Cardiff gets underway at 8:45 PM UAE time.
Meanwhile Scotland travel to France for their latest Six Nations fixture.
Action from the Stade de France starts at 6:15 PM UAE time.
Daniil Medvedev handed Dubai title after Griekspoor withdrawal
Daniil Medvedev has been awarded the Dubai Duty Free Tennis Championships title on Saturday afternoon after Tallon Griekspoor was forced to withdraw due to an injury.
England beat New Zealand to keep Pakistan's T20 World Cup hopes alive
Rehan Ahmed and Will Jacks' rapid 44-run partnership turned the game as England chased down a target of 160 with three balls to spare and beat New Zealand by four wickets in the Twenty20 World Cup Super Eights on Friday.
Medvedev to face Griekspoor in bid for second Dubai title
Daniil Medvedev reached the Dubai Duty Free Tennis Championships final on Friday and will face unseeded Tallon Griekspoor as the Russian attempts to achieve something that has eluded him throughout his stellar career - winning the same tournament twice.
Real Madrid face Man City again in Champions League knockouts
Manchester City were drawn against Real Madrid in the Champions League knockout phase for the sixth time since the 2019-20 season after the draw for the last 16, quarter-finals and semi-finals was made on Friday.
India defeat Zimbabwe to revive T20 World Cup hopes
A rampant India piled up a record total and handed Zimbabwe a 72‑run thrashing in a Super Eight contest on Thursday to revive their Twenty20 World Cup title defence.
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