Jason Roy and captain Joe Root both smashed centuries as the tourists easily reached their target of 361 with eight balls to spare in Barbados.
It was their highest ever run-chase in the format.
Chris Gayle's innings of 139 off 129 balls went in vain as the Windies' poor form in ODI cricket continued.
The second encounter of the five-match series will be played on Friday.
Ronaldo on target as Al-Nassr win after security delay
Cristiano Ronaldo has scored Al-Nassr's second goal as the Saudi Pro League champions overcame an hour-long security delay to beat Uzbekistan's Neftchi 3-1 in the AFC Champions League Elite on Monday.
Coventry savour first home Premier League win in 25 years
Coventry City appear to have found their feet in the Premier League after claiming their first home win of the season with a thumping 4-1 victory over Newcastle United on Monday.
Bergs shocks Alcaraz in Shanghai as Zverev claims year-end top ranking
Seven-times Grand Slam champion Carlos Alcaraz suffered a shock 7-5 7-6(4) defeat by unseeded Belgian Zizou Bergs in the Shanghai Masters round of 32 on Monday, a result that also confirmed Alexander Zverev as the ATP's year-end world number one.
Ten arrested and police officer injured after Manchester City’s win at Liverpool
Ten people were arrested and a police officer suffered a serious facial injury after crowd trouble at Manchester City’s 3-0 Premier League win at Liverpool on Sunday, Merseyside Police said on Monday.
Australia need six wickets on final day to win first Test
Australia’s Matt Renshaw played a leading role to leave his side needing six wickets on the last day of the first Test to beat South Africa as the hosts were 102-4 at the close of play at Kingsmead on Monday.
6:00am - 10:00am
Kris, Priti and Rossi host the UAE's biggest radio show. It's full of fun, laughs and it's Where The Stars Live.
Let Me Be <Kfs>
The Second Voice & Elvin Cena
Loser
Tame Impala
Cheerleader
Omi