England bowled West Indies out for 45 - the second lowest total in international Twenty20 history - to win by 137 runs in St Kitts.
Joe Root's 55 runs and Sam Billings' brilliant knock of 87 off 47 balls helped to win with ease, taking an unassailable 2-0 lead in the series.
This is England's biggest margin of victory by runs in T20s and the fourth biggest of all time.
The final T20 will be played in St Kitts at 20:00 GMT on Sunday.
Gill smashes fastest ODI double century as India beat West Indies
Shubman Gill struck the fastest double century in one-day international history as India completed the second-highest successful chase in an ODI with an eight-wicket victory over West Indies in the second match of the three-game series in Guwahati on Wednesday.
UAE Cup winner Carruthers takes Abu Dhabi Challenge lead
Australia's Coby Carruthers made the most of an invitation from the Emirates Golf Federation (EGF) as he shot a bogey-free eight-under-par 62 to lead the Abu Dhabi Challenge after the opening round at Al Ain Equestrian, Shooting & Golf Club.
2027 London Marathon dates decided by game of rock-paper-scissors
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Lamine nets double as Spain win again, England beat 10-man Czechs
Lamine Yamal has scored twice as World Cup winners Spain extended their unbeaten run to 40 matches and maintained their perfect start to Nations League Group A3 with a 4-1 home win over Croatia on Tuesday, while England overcame 10-man Czech Republic 2-0 in Prague.
Dubai-based Horsey eyes DP World Tour return as strong UAE contingent heads to Al Ain
Four-time DP World Tour winner David Horsey heads a strong UAE-based contingent when the Abu Dhabi Challenge gets under way at Al Ain Equestrian, Shooting & Golf Club on Wednesday, with a return to the DP World Tour within touching distance.
