Inter Miami star captain Lionel Messi appeared to suffer a leg injury after grabbing his left thigh, forcing him out in the 73rd minute of a 6-4 home victory over the Philadelphia Union on Sunday night.
In the 70th minute, the two-time reigning MLS MVP could be seen grabbing at the upper section of his left thigh following a free kick.
The Argentine legend requested a substitution, then headed to the locker room after Mateo Silvetti replaced him.
Messi, 38, who has a league-leading 20 goal contributions (12 goals, eight assists) in 14 matches this season, was able to get up and leave the field under his own power. In his fourth season with Inter Miami, Messi has 107 goal contributions (62 goals, 45 assists) in 67 games (59 starts).
MLS began a six-week break after Sunday's matches, with the FIFA World Cup set to begin June 11 and run through July 19.
Messi is expected to play for Argentina, the defending World Cup champions, though this year's squad has yet to be announced.
Argentina's first match in Group J play is June 16 against Algeria in Kansas City.
Argentina will prep for group stage play with friendlies against Honduras on June 6 at Texas A&M's Kyle Field and Iceland on June 9 at Auburn's Jordan-Hare Stadium.
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