Spain's top court has sent Belgium an arrest warrant for Catalonia's former pro-independence leader Carles Puigdemont.
It comes days after the Spanish Supreme Court sentenced nine Catalan leaders to jail terms ranging from 9-13 years for sedition.
Belgium had earlier turned down Spain's requests, first in 2017 and then in 2018.
Puigdemont went into self-imposed exile in Belgium in autumn 2017 after Catalan separatist leaders organised a referendum that Spanish courts had ruled illegal.
"Considering the complexity of the file and the two European arrest warrants previously sent against Mr. Puigdemont, the case will require a thorough judicial analysis," The Brussels prosecutor's spokeswoman said on Wednesday.
It may take weeks to reach a decision, she said, adding that the key issue for local authorities would be to decide if the convictions for sedition were legally recognised in Belgium.

Britain working with allies to support shipping through Strait of Hormuz
Five Iranian women's soccer players granted humanitarian visas in Australia
Almost 700,000 displaced after Israeli strikes on Lebanon, UN agencies say
Iran fighting back but not stronger than U.S. thought, top U.S. general says
British warship HMS Dragon departs for Eastern Mediterranean