London Fire Brigade on Monday said it was tackling a fire on the 17th floor of a high-rise apartment block in the east of the city.
A video shared on Twitter by the fire brigade showed a orange flames and smoke pouring out of a high-rise building.
"Twenty fire engines are now at the scene of the #Whitechapel High Street fire which is in a block of flats and offices," London Fire Brigade said on Twitter.
The London Ambulance Service said that it was also responding to the fire.
"If you are in the local area, please try and stay indoors and keep windows and doors closed," it said.
Twenty fire engines are now at the scene of the #Whitechapel fire which is in a block of flats and offices. Our Control Officers have taken more than 50 calls to the blaze © @dinglebobs https://t.co/wyMmpNeYbp pic.twitter.com/ijiW2WNOg8— London Fire Brigade (@LondonFire) March 7, 2022