With almost 14 million followers, Madonna thinks Instagram is designed to "make you feel bad".
The 60-year-old admitted that social media's influence can also be toxic.
"You get caught up in comparing yourself to others. I think Instagram is made to make you feel bad. People are really a slave to winning people's approvals," she explained.
Madonna thinks she's fortunate to have found fame in the pre-internet era.
As a result, the chart-topping singer believes she was given the scope to "develop as an artist and a human without feeling the pressure of judgement of other people".

Son of filmmaker Rob Reiner appears in court on charges he murdered parents
Warner Bros Discovery board rejects rival bid from Paramount
Filmmaker Rob Reiner's son charged with murder in parents' slaying
Second doctor in Matthew Perry overdose case sentenced to home confinement
Son of filmmaker Rob Reiner jailed on suspicion of murdering parents
Seven New Year countdowns to light up Global Village