Pope Francis on Sunday called for an Easter truce in Ukraine, and in an apparent reference to Russia, questioned the value of planting a victory flag "on a heap of rubble".
Pope Francis spoke at the end of a Palm Sunday service for about 50,000 people in St. Peter's Square, the first time since 2019 that the public was allowed to attend following two years of scaled back services because of COVID-19 restrictions.
"Put the weapons down! Let An Easter truce start. But not to re-arm and resume combat but a truce to reach peace through real negotiations open to some sacrifices for the good of the people," he said.
A flare-up of pain in his knee forced Francis, 85, to skip the traditional procession from the obelisk at the centre of the square to the altar on the steps of St. Peter's Basilica.
He watched instead while seated at the altar and later limped as he said the Mass.
Francis earlier evoked the horrors of war in his sermon, speaking of "mothers who mourn the unjust death of husbands and sons...refugees who flee from bombs with children in their arms...young people deprived of a future...soldiers sent to kill their brothers and sisters".
Iran and Israel targeted each other with missiles and airstrikes early on Saturday after Israel launched its biggest-ever air offensive against its longtime foe in a bid to prevent it from developing a nuclear weapon.
Israeli fire and airstrikes killed at least 35 Palestinians across the Gaza Strip, most of them near an aid distribution site operated by the US-backed Gaza Humanitarian Foundation, local health authorities said.
The death toll from the Air India plane crash in Ahmedabad rose to 270 on Saturday, as grieving families expressed frustration over delays in the release of victims' bodies, many of which were badly charred in the tragedy.
US President Donald Trump urged Iran on Friday to make a deal on its nuclear programme before it faced more attacks from Israel that he said would be "even more brutal."
Israel launched widescale strikes against Iran on Friday, saying it targeted nuclear facilities, ballistic missile factories and military commanders and that this was start of a prolonged operation to prevent Tehran from building an atomic weapon.