Political newcomer Robert Abela is set to take over from Joseph Muscat following Saturday's vote.
Election results, which was revealed on Sunday, handed the leader of the ruling Labour Party 58 per cent of the votes.
He defeated initial favourite - deputy prime minister and minister of health Chris Fearne.
"I am humbled," Abela told supporters. "I thank my friend Chris (Fearne) and look forward to working together for the good of the party and the country. There is only one winner today, the Labour Party."
Abela, who was elected to the parliament for the first time just over two years ago, has promised to place increased government focus on social issues and affordable housing.
Muscat, who announced his resignation on December 1, has been accused of protecting associates involved in the 2017 murder of journalist Daphne Caruana Galizia.
Prince Harry said on Friday that he wanted reconciliation with the British royal family but his father King Charles will not speak to him over a row over his security and he did not know how long the monarch, who has cancer, would live.
A magnitude 7.4 earthquake struck Drake Passage between Cape Horn and Antarctica at a depth of 10 km (6 miles) on Friday, the United States Geological Survey said.
A ship with humanitarian aid and activists for Gaza was bombed by drones while in international waters off Malta early on Friday, its organisers said, and the Maltese government said after a rescue operation that everyone on board was safe.
A power outage hit several regions of Indonesia's resort island of Bali on Friday and efforts were underway to restore services to those affected, state utility Perusahaan Listrik Negara said.
A Russian drone attack late on Thursday set buildings ablaze in Ukraine's southeastern city of Zaporizhzhia, injuring 29 people, regional governor Ivan Fedorov said.